BDBM50000670 8-Methoxy-4-o-tolylamino-quinoline-2-carboxylic acid ethyl ester::CHEMBL51901

SMILES: CCOC(=O)c1cc(Nc2ccccc2C)c2cccc(OC)c2n1

InChI Key: InChIKey=METYVFXHJAMDEE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase alpha chain 1/beta chain (Rattus norvegicus)	BDBM50000670 (8-Methoxy-4-o-tolylamino-quinoline-2-carboxylic ac...) Show SMILES CCOC(=O)c1cc(Nc2ccccc2C)c2cccc(OC)c2n1 Show InChI InChI=1S/C20H20N2O3/c1-4-25-20(23)17-12-16(21-15-10-6-5-8-13(15)2)14-9-7-11-18(24-3)19(14)22-17/h5-12H,4H2,1-3H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Inhibition of rat isolated gastric(H+/K+)-ATPase.				J Med Chem 35: 1845-52 (1992) BindingDB Entry DOI: 10.7270/Q2SQ8ZB3
					More data for this Ligand-Target Pair