BDBM50000785 2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrolidin-1-yl-cyclohexyl)-acetamide::CHEMBL74010

SMILES: CN([C@H]1CC(=O)CC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=PXDHKHOBECBLPH-ROUUACIJSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50000785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50000785 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrol...) Show SMILES CN([C@H]1CC(=O)CC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H24Cl2N2O2/c1-22(19(25)11-13-4-6-15(20)16(21)10-13)18-12-14(24)5-7-17(18)23-8-2-3-9-23/h4,6,10,17-18H,2-3,5,7-9,11-12H2,1H3/t17-,18-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa from guinea pig brain membranes using [3H]ethylketocyclazocine as radioligand				J Med Chem 35: 2243-7 (1992) BindingDB Entry DOI: 10.7270/Q20K296N
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50000785 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrol...) Show SMILES CN([C@H]1CC(=O)CC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H24Cl2N2O2/c1-22(19(25)11-13-4-6-15(20)16(21)10-13)18-12-14(24)5-7-17(18)23-8-2-3-9-23/h4,6,10,17-18H,2-3,5,7-9,11-12H2,1H3/t17-,18-/m0/s1	UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity against opioid receptor mu from guinea pig brain membranes using [3H]naloxone as radioligand				J Med Chem 35: 2243-7 (1992) BindingDB Entry DOI: 10.7270/Q20K296N
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50000785 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(5-oxo-2-pyrrol...) Show SMILES CN([C@H]1CC(=O)CC[C@@H]1N1CCCC1)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H24Cl2N2O2/c1-22(19(25)11-13-4-6-15(20)16(21)10-13)18-12-14(24)5-7-17(18)23-8-2-3-9-23/h4,6,10,17-18H,2-3,5,7-9,11-12H2,1H3/t17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity against opioid receptor delta from guinea pig brain membranes using [3H]DADLE as radioligand				J Med Chem 35: 2243-7 (1992) BindingDB Entry DOI: 10.7270/Q20K296N
					More data for this Ligand-Target Pair