BDBM50000960 CHEMBL3228814

SMILES: CN(C)C(C)(C)Cn1c2nc(C)cc(C)c2ccc1=O

InChI Key: InChIKey=LOJYXGAEYJPAGA-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H2 receptor (RAT)	BDBM50000960 (CHEMBL3228814) Show SMILES CN(C)C(C)(C)Cn1c2nc(C)cc(C)c2ccc1=O Show InChI InChI=1S/C16H23N3O/c1-11-9-12(2)17-15-13(11)7-8-14(20)19(15)10-16(3,4)18(5)6/h7-9H,10H2,1-6H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Antagonist activity at histamine H2 receptor in Charles River rat assessed as inhibition of histamine-mediated electrically stimulated uterine contra...				J Med Chem 22: 301-6 (1979) BindingDB Entry DOI: 10.7270/Q25140QF
					More data for this Ligand-Target Pair