BDBM50001057 CHEMBL3236008

SMILES: COc1cccc(c1)C(=O)c1ccn(c1)-c1ccc(O)c(F)c1

InChI Key: InChIKey=PGMKFDQBEICKFA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (Rattus norvegicus)	BDBM50001057 (CHEMBL3236008) Show SMILES COc1cccc(c1)C(=O)c1ccn(c1)-c1ccc(O)c(F)c1 Show InChI InChI=1S/C18H14FNO3/c1-23-15-4-2-3-12(9-15)18(22)13-7-8-20(11-13)14-5-6-17(21)16(19)10-14/h2-11,21H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Aristotle University of Thessaloniki Curated by ChEMBL					Assay Description Inhibition of Fischer-344 rat kidney ALR1 using D-glucuronate as substrate by spectrophotometry				Bioorg Med Chem 22: 2194-207 (2014) Article DOI: 10.1016/j.bmc.2014.02.016 BindingDB Entry DOI: 10.7270/Q2CJ8G0C
					More data for this Ligand-Target Pair