BindingDB logo
myBDB logout

null

SMILES: Oc1ccc(cc1F)-n1cc(cc1C(=O)C(F)F)C(=O)c1ccccc1

InChI Key: InChIKey=UVEABFPADXQPTH-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001061   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Rattus norvegicus)		BDBM50001061
PNG
(CHEMBL3236020)
Show SMILES Oc1ccc(cc1F)-n1cc(cc1C(=O)C(F)F)C(=O)c1ccccc1
Show InChI InChI=1S/C19H12F3NO3/c20-14-9-13(6-7-16(14)24)23-10-12(8-15(23)18(26)19(21)22)17(25)11-4-2-1-3-5-11/h1-10,19,24H
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.21E+4n/an/an/an/an/an/a



Aristotle University of Thessaloniki

Curated by ChEMBL


Assay Description
Inhibition of Fischer-344 rat kidney ALR1 using D-glucuronate as substrate by spectrophotometry

Bioorg Med Chem 22: 2194-207 (2014)


Article DOI: 10.1016/j.bmc.2014.02.016
BindingDB Entry DOI: 10.7270/Q2CJ8G0C
More data for this
Ligand-Target Pair