BDBM50001239 CHEMBL116272::Cyclobutyl-(8-methoxy-4-o-tolylamino-quinolin-3-yl)-methanone

SMILES: COc1cccc2c(Nc3ccccc3C)c(cnc12)C(=O)C1CCC1

InChI Key: InChIKey=ZNTDOPFZLXOXLH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50001239   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium-transporting ATPase (Sus scrofa (Pig))	BDBM50001239 (CHEMBL116272 | Cyclobutyl-(8-methoxy-4-o-tolylamin...) Show SMILES COc1cccc2c(Nc3ccccc3C)c(cnc12)C(=O)C1CCC1 Show InChI InChI=1S/C22H22N2O2/c1-14-7-3-4-11-18(14)24-20-16-10-6-12-19(26-2)21(16)23-13-17(20)22(25)15-8-5-9-15/h3-4,6-7,10-13,15H,5,8-9H2,1-2H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals R&D Curated by ChEMBL					Assay Description Concentration required to inhibit the activity of K+ stimulated gastric ATPase				J Med Chem 35: 3413-22 (1992) BindingDB Entry DOI: 10.7270/Q2CN74J2
					More data for this Ligand-Target Pair