BDBM50001995 2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-piperidin-1-yl}-ethanol::CHEMBL430151

SMILES: OCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12

InChI Key: InChIKey=ANOQQUDEPUAIRE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50001995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...)	BDBM50001995 (2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-...) Show SMILES OCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C21H22ClFN2O/c22-16-1-6-21-19(13-16)20(15-7-9-24(10-8-15)11-12-26)14-25(21)18-4-2-17(23)3-5-18/h1-6,13-15,26H,7-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Inhibition of [3H]ketanserin binding to rat 5-hydroxytryptamine 2 receptors.				J Med Chem 35: 1092-101 (1992) BindingDB Entry DOI: 10.7270/Q2Z89BB3
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001995 (2-{4-[5-Chloro-1-(4-fluoro-phenyl)-1H-indol-3-yl]-...) Show SMILES OCCN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C21H22ClFN2O/c22-16-1-6-21-19(13-16)20(15-7-9-24(10-8-15)11-12-26)14-25(21)18-4-2-17(23)3-5-18/h1-6,13-15,26H,7-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Tested for the inhibition of [3H]-spiperone binding to dopamine D2 receptor				J Med Chem 35: 1092-101 (1992) BindingDB Entry DOI: 10.7270/Q2Z89BB3
					More data for this Ligand-Target Pair