BDBM50002257 4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-benzonitrile::CHEMBL46463

SMILES: N#Cc1ccc(OCC2CCN(CC3CC3)CC2)cc1

InChI Key: InChIKey=IOFBNVAOCHKHPO-UHFFFAOYSA-N

Data: 3 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50002257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50002257 (4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-benz...) Show SMILES N#Cc1ccc(OCC2CCN(CC3CC3)CC2)cc1 Show InChI InChI=1S/C17H22N2O/c18-11-14-3-5-17(6-4-14)20-13-16-7-9-19(10-8-16)12-15-1-2-15/h3-6,15-16H,1-2,7-10,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ANSTO Curated by ChEMBL					Assay Description Receptor binding affinity against Sigma receptor				J Med Chem 40: 1657-67 (1997) Article DOI: 10.1021/jm960720+ BindingDB Entry DOI: 10.7270/Q29G5KX8
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Mus musculus (Mouse))	BDBM50002257 (4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-benz...) Show SMILES N#Cc1ccc(OCC2CCN(CC3CC3)CC2)cc1 Show InChI InChI=1S/C17H22N2O/c18-11-14-3-5-17(6-4-14)20-13-16-7-9-19(10-8-16)12-15-1-2-15/h3-6,15-16H,1-2,7-10,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for the mouse sigma opioid receptor				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Mus musculus (Mouse))	BDBM50002257 (4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-benz...) Show SMILES N#Cc1ccc(OCC2CCN(CC3CC3)CC2)cc1 Show InChI InChI=1S/C17H22N2O/c18-11-14-3-5-17(6-4-14)20-13-16-7-9-19(10-8-16)12-15-1-2-15/h3-6,15-16H,1-2,7-10,12-13H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Mus musculus (Mouse))	BDBM50002257 (4-(1-Cyclopropylmethyl-piperidin-4-ylmethoxy)-benz...) Show SMILES N#Cc1ccc(OCC2CCN(CC3CC3)CC2)cc1 Show InChI InChI=1S/C17H22N2O/c18-11-14-3-5-17(6-4-14)20-13-16-7-9-19(10-8-16)12-15-1-2-15/h3-6,15-16H,1-2,7-10,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D2				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair