BDBM50002759 5-(2-Benzenesulfonylamino-ethylsulfanyl)-5,11-dihydro-10-thia-dibenzo[a,d]cycloheptene-7-carboxylic acid::CHEMBL114901

SMILES: OC(=O)c1ccc2SCc3ccccc3C(SCCNS(=O)(=O)c3ccccc3)c2c1

InChI Key: InChIKey=KQCDAMXNJBCRPM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50002759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50002759 (5-(2-Benzenesulfonylamino-ethylsulfanyl)-5,11-dihy...) Show SMILES OC(=O)c1ccc2SCc3ccccc3C(SCCNS(=O)(=O)c3ccccc3)c2c1 Show InChI InChI=1S/C23H21NO4S3/c25-23(26)16-10-11-21-20(14-16)22(19-9-5-4-6-17(19)15-30-21)29-13-12-24-31(27,28)18-7-2-1-3-8-18/h1-11,14,22,24H,12-13,15H2,(H,25,26)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Company, Ltd. Curated by ChEMBL					Assay Description Inhibition of Shh signaling in mouse Shh-light2 cells by Gli-dependent firefly luciferase reporter gene assay				J Med Chem 35: 3394-402 (1992) BindingDB Entry DOI: 10.7270/Q2NS0SV5
					More data for this Ligand-Target Pair
Prostanoid TP receptor (Homo sapiens (Human))	BDBM50002759 (5-(2-Benzenesulfonylamino-ethylsulfanyl)-5,11-dihy...) Show SMILES OC(=O)c1ccc2SCc3ccccc3C(SCCNS(=O)(=O)c3ccccc3)c2c1 Show InChI InChI=1S/C23H21NO4S3/c25-23(26)16-10-11-21-20(14-16)22(19-9-5-4-6-17(19)15-30-21)29-13-12-24-31(27,28)18-7-2-1-3-8-18/h1-11,14,22,24H,12-13,15H2,(H,25,26)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Company, Ltd. Curated by ChEMBL					Assay Description Binding affinity at TXA2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig platelets				J Med Chem 35: 3394-402 (1992) BindingDB Entry DOI: 10.7270/Q2NS0SV5
					More data for this Ligand-Target Pair