BDBM50003397 2-Methyl-4-{2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl]-vinyl}-quinoline::CHEMBL336056

SMILES: Cc1cc(C=Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2ccccc2n1

InChI Key: InChIKey=UVEACIMNWJCOEQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Type-1 angiotensin II receptor (Cavia porcellus)	BDBM50003397 (2-Methyl-4-{2-[2'-(1H-tetrazol-5-yl)-biphenyl-4-yl...) Show SMILES Cc1cc(C=Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)c2ccccc2n1 |w:4.3| Show InChI InChI=1S/C25H19N5/c1-17-16-20(22-7-4-5-9-24(22)26-17)15-12-18-10-13-19(14-11-18)21-6-2-3-8-23(21)25-27-29-30-28-25/h2-16H,1H3,(H,27,28,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparation				J Med Chem 35: 4027-38 (1992) BindingDB Entry DOI: 10.7270/Q2G44P8Q
					More data for this Ligand-Target Pair