BDBM50003731 CHEMBL3235297

SMILES: Cc1ccc(cc1)C1=Nc2c(N)ncnc2OC1(C)C

InChI Key: InChIKey=VYSUKSJUEGJUFY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50003731 (CHEMBL3235297) Show SMILES Cc1ccc(cc1)C1=Nc2c(N)ncnc2OC1(C)C |t:8| Show InChI InChI=1S/C15H16N4O/c1-9-4-6-10(7-5-9)12-15(2,3)20-14-11(19-12)13(16)17-8-18-14/h4-8H,1-3H3,(H2,16,17,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPA				J Med Chem 57: 3464-83 (2014) Article DOI: 10.1021/jm500135c BindingDB Entry DOI: 10.7270/Q23X886W
					More data for this Ligand-Target Pair