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SMILES: CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)c1SCC

InChI Key: InChIKey=YBMSMYKJMQQYGZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50003912   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))		BDBM50003912
PNG
(CHEMBL3235706)
Show SMILES CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)c1SCC
Show InChI InChI=1S/C23H34N4S/c1-7-11-27(14-19-9-10-19)23-21(28-8-2)22(24-18(6)25-23)26-20-16(4)12-15(3)13-17(20)5/h12-13,19H,7-11,14H2,1-6H3,(H,24,25,26)
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n/an/a 245n/an/an/an/an/an/a



South Dakota State University

Curated by ChEMBL


Assay Description
Displacement of [125I]Tyr0sauvagine from human CRF1 receptor expressed in HEK293 cell membrane after 120 mins by gamma scintillation counting analysi...

Eur J Med Chem 78: 1-9 (2014)


Article DOI: 10.1016/j.ejmech.2014.03.040
BindingDB Entry DOI: 10.7270/Q2VD710K
More data for this
Ligand-Target Pair