BDBM50004099 CHEMBL3236122

SMILES: NC[C@H]1CN(CCc2ccncc2)C(=O)C[C@@H]1c1cc(F)c(F)cc1F

InChI Key: InChIKey=JQBDYKZHPXTXJN-KBPBESRZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004099   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50004099 (CHEMBL3236122) Show SMILES NC[C@H]1CN(CCc2ccncc2)C(=O)C[C@@H]1c1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C19H20F3N3O/c20-16-9-18(22)17(21)7-15(16)14-8-19(26)25(11-13(14)10-23)6-3-12-1-4-24-5-2-12/h1-2,4-5,7,9,13-14H,3,6,8,10-11,23H2/t13-,14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
M.S. University of Baroda Curated by ChEMBL					Assay Description Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysis				Bioorg Med Chem Lett 24: 1918-22 (2014) Article DOI: 10.1016/j.bmcl.2014.03.009 BindingDB Entry DOI: 10.7270/Q2G73G7F
					More data for this Ligand-Target Pair