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SMILES: NC[C@H]1CN(CCc2ccncc2)C(=O)C[C@@H]1c1ccc(Cl)cc1Cl

InChI Key: InChIKey=RGBZYYBIBZYQFP-YOEHRIQHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50004104   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50004104
PNG
(CHEMBL3236127)
Show SMILES NC[C@H]1CN(CCc2ccncc2)C(=O)C[C@@H]1c1ccc(Cl)cc1Cl |r|
Show InChI InChI=1S/C19H21Cl2N3O/c20-15-1-2-16(18(21)9-15)17-10-19(25)24(12-14(17)11-22)8-5-13-3-6-23-7-4-13/h1-4,6-7,9,14,17H,5,8,10-12,22H2/t14-,17-/m0/s1
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n/an/a 197n/an/an/an/an/an/a



M.S. University of Baroda

Curated by ChEMBL


Assay Description
Inhibition of human DPP-4 expressed in baculovirus expression system using H-Gly-Pro-AMC as substrate after 30 mins by fluorometric analysis

Bioorg Med Chem Lett 24: 1918-22 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.009
BindingDB Entry DOI: 10.7270/Q2G73G7F
More data for this
Ligand-Target Pair