BDBM50004897 (APV)2-Amino-5-phosphono-pentanoic acid::(R)-2-Amino-5-phosphono-pentanoic acid::(R)-2-amino-5-phosphonopentanoicacid::2-Amino-5-phosphono-pentanoic acid::2-Amino-5-phosphono-pentanoic acid anion::2-Amino-5-phosphono-pentanoic acid(D-AP5)::2-Amino-5-phosphono-pentanoic acid(R-AP5)::2-Amino-5-phosphono-pentanoic acid(S-AP5)::CHEMBL28862::DL-2-amino-5-phosphono valericacid::DL-2-amino-5-phosphonovaleric acid

SMILES: NC(CCCP(O)(O)=O)C(O)=O

InChI Key: InChIKey=VOROEQBFPPIACJ-UHFFFAOYSA-N

Data: 5 KI

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50004897   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50004897 ((APV)2-Amino-5-phosphono-pentanoic acid | (R)-2-Am...) Show SMILES NC(CCCP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2A expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50004897 ((APV)2-Amino-5-phosphono-pentanoic acid | (R)-2-Am...) Show SMILES NC(CCCP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2B expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate [NMDA] receptor subunit epsilon 3/zeta 1 (RAT-Rattus norvegicus (Rat))	BDBM50004897 ((APV)2-Amino-5-phosphono-pentanoic acid | (R)-2-Am...) Show SMILES NC(CCCP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Walk Curated by ChEMBL					Assay Description Inhibitory constant against (S)-glutamate and glycine evoked currents mediated by N-methyl-D-aspartate glutamate receptor NR1a/NR2C expressed in Xeno...				J Med Chem 48: 2627-37 (2005) Article DOI: 10.1021/jm0492498 BindingDB Entry DOI: 10.7270/Q2FJ2G89
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, kainate (Rattus norvegicus)	BDBM50004897 ((APV)2-Amino-5-phosphono-pentanoic acid | (R)-2-Am...) Show SMILES NC(CCCP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merrell Dow Research Institute Curated by ChEMBL					Assay Description Binding affinity towards Ionotropic glutamate receptor kainate using [3H]-kainic acid as radioligand; Inactive				J Med Chem 33: 2961-3 (1990) BindingDB Entry DOI: 10.7270/Q2BK1CXM
					More data for this Ligand-Target Pair
Glutamate receptor 1 (Rattus norvegicus (Rat))	BDBM50004897 ((APV)2-Amino-5-phosphono-pentanoic acid | (R)-2-Am...) Show SMILES NC(CCCP(O)(O)=O)C(O)=O Show InChI InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merrell Dow Research Institute Curated by ChEMBL					Assay Description Binding affinity towards AMPA receptor using [3H]AMPA as radioligand; Inactive				J Med Chem 33: 2961-3 (1990) BindingDB Entry DOI: 10.7270/Q2BK1CXM
					More data for this Ligand-Target Pair