BDBM50005038 5,7-Dichloro-4-(3-m-tolyl-ureido)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL61313

SMILES: Cc1cccc(NC(=O)N[C@H]2C[C@@H](Nc3cc(Cl)cc(Cl)c23)C(O)=O)c1

InChI Key: InChIKey=KFPJTANOVZYLIQ-LSDHHAIUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005038   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005038 (5,7-Dichloro-4-(3-m-tolyl-ureido)-1,2,3,4-tetrahyd...) Show SMILES Cc1cccc(NC(=O)N[C@H]2C[C@@H](Nc3cc(Cl)cc(Cl)c23)C(O)=O)c1 Show InChI InChI=1S/C18H17Cl2N3O3/c1-9-3-2-4-11(5-9)21-18(26)23-14-8-15(17(24)25)22-13-7-10(19)6-12(20)16(13)14/h2-7,14-15,22H,8H2,1H3,(H,24,25)(H2,21,23,26)/t14-,15+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair