BDBM50005045 5,7-Dichloro-4-(4-phenyl-butyrylamino)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL57937

SMILES: OC(=O)[C@H]1C[C@H](NC(=O)CCCc2ccccc2)c2c(Cl)cc(Cl)cc2N1

InChI Key: InChIKey=DBAWGZLWFPLLGA-DLBZAZTESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005045   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005045 (5,7-Dichloro-4-(4-phenyl-butyrylamino)-1,2,3,4-tet...) Show SMILES OC(=O)[C@H]1C[C@H](NC(=O)CCCc2ccccc2)c2c(Cl)cc(Cl)cc2N1 Show InChI InChI=1S/C20H20Cl2N2O3/c21-13-9-14(22)19-15(10-13)23-17(20(26)27)11-16(19)24-18(25)8-4-7-12-5-2-1-3-6-12/h1-3,5-6,9-10,16-17,23H,4,7-8,11H2,(H,24,25)(H,26,27)/t16-,17+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair