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BDBM50005054 5,7-Dichloro-4-(3,3-diphenyl-ureido)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL62092

SMILES: OC(=O)[C@H]1C[C@H](NC(=O)N(c2ccccc2)c2ccccc2)c2c(Cl)cc(Cl)cc2N1

InChI Key: InChIKey=OAJRZAZPPHZOAF-VQTJNVASSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005054   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50005054
PNG
(5,7-Dichloro-4-(3,3-diphenyl-ureido)-1,2,3,4-tetra...)
Show SMILES OC(=O)[C@H]1C[C@H](NC(=O)N(c2ccccc2)c2ccccc2)c2c(Cl)cc(Cl)cc2N1
Show InChI InChI=1S/C23H19Cl2N3O3/c24-14-11-17(25)21-18(12-14)26-20(22(29)30)13-19(21)27-23(31)28(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-12,19-20,26H,13H2,(H,27,31)(H,29,30)/t19-,20+/m0/s1
PDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 19n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.

J Med Chem 35: 1954-68 (1992)


BindingDB Entry DOI: 10.7270/Q2T72GCZ
More data for this
Ligand-Target Pair