BDBM50005056 5,7-Dichloro-4-(2-oxo-pyrrolidin-1-yl)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL302427

SMILES: OC(=O)[C@H]1C[C@H](N2CCCC2=O)c2c(Cl)cc(Cl)cc2N1

InChI Key: InChIKey=HVVGVECEQTYTJB-MNOVXSKESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005056   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005056 (5,7-Dichloro-4-(2-oxo-pyrrolidin-1-yl)-1,2,3,4-tet...) Show SMILES OC(=O)[C@H]1C[C@H](N2CCCC2=O)c2c(Cl)cc(Cl)cc2N1 Show InChI InChI=1S/C14H14Cl2N2O3/c15-7-4-8(16)13-9(5-7)17-10(14(20)21)6-11(13)18-3-1-2-12(18)19/h4-5,10-11,17H,1-3,6H2,(H,20,21)/t10-,11+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair