BDBM50005059 5,7-Dichloro-4-(3-methyl-3-phenyl-ureido)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL60017

SMILES: CN(C(=O)N[C@H]1C[C@@H](Nc2cc(Cl)cc(Cl)c12)C(O)=O)c1ccccc1

InChI Key: InChIKey=VWMLIPRIVKIQAE-LSDHHAIUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005059 (5,7-Dichloro-4-(3-methyl-3-phenyl-ureido)-1,2,3,4-...) Show SMILES CN(C(=O)N[C@H]1C[C@@H](Nc2cc(Cl)cc(Cl)c12)C(O)=O)c1ccccc1 Show InChI InChI=1S/C18H17Cl2N3O3/c1-23(11-5-3-2-4-6-11)18(26)22-14-9-15(17(24)25)21-13-8-10(19)7-12(20)16(13)14/h2-8,14-15,21H,9H2,1H3,(H,22,26)(H,24,25)/t14-,15+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair