BDBM50005063 5,7-Dichloro-4-(3-phenyl-thioureido)-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL294561

SMILES: OC(=O)[C@H]1C[C@H](NC(=S)Nc2ccccc2)c2c(Cl)cc(Cl)cc2N1

InChI Key: InChIKey=NXURUXHHGGAABF-UONOGXRCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005063 (5,7-Dichloro-4-(3-phenyl-thioureido)-1,2,3,4-tetra...) Show SMILES OC(=O)[C@H]1C[C@H](NC(=S)Nc2ccccc2)c2c(Cl)cc(Cl)cc2N1 Show InChI InChI=1S/C17H15Cl2N3O2S/c18-9-6-11(19)15-12(7-9)21-14(16(23)24)8-13(15)22-17(25)20-10-4-2-1-3-5-10/h1-7,13-14,21H,8H2,(H,23,24)(H2,20,22,25)/t13-,14+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair