BDBM50005064 4-(3-Benzyl-ureido)-5,7-dichloro-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL294043

SMILES: OC(=O)[C@H]1C[C@H](NC(=O)NCc2ccccc2)c2c(Cl)cc(Cl)cc2N1

InChI Key: InChIKey=VOFSYTJPDIFPCK-LSDHHAIUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005064 (4-(3-Benzyl-ureido)-5,7-dichloro-1,2,3,4-tetrahydr...) Show SMILES OC(=O)[C@H]1C[C@H](NC(=O)NCc2ccccc2)c2c(Cl)cc(Cl)cc2N1 Show InChI InChI=1S/C18H17Cl2N3O3/c19-11-6-12(20)16-13(7-11)22-15(17(24)25)8-14(16)23-18(26)21-9-10-4-2-1-3-5-10/h1-7,14-15,22H,8-9H2,(H,24,25)(H2,21,23,26)/t14-,15+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair