BDBM50005071 5,7-Dichloro-4-[(pyridine-4-carbonyl)-amino]-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid::CHEMBL58966

SMILES: OC(=O)[C@H]1C[C@H](NC(=O)c2ccncc2)c2c(Cl)cc(Cl)cc2N1

InChI Key: InChIKey=OHISFQIMSUZDPS-QWHCGFSZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005071   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005071 (5,7-Dichloro-4-[(pyridine-4-carbonyl)-amino]-1,2,3...) Show SMILES OC(=O)[C@H]1C[C@H](NC(=O)c2ccncc2)c2c(Cl)cc(Cl)cc2N1 Show InChI InChI=1S/C16H13Cl2N3O3/c17-9-5-10(18)14-11(6-9)20-13(16(23)24)7-12(14)21-15(22)8-1-3-19-4-2-8/h1-6,12-13,20H,7H2,(H,21,22)(H,23,24)/t12-,13+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair