BDBM50005089 4-anilino(imino-N-cyano)methylamino-5,7-dichloro-(2R,4S)-1,2,3,4-tetrahydro-2-quinolinecarboxylic acid::CHEMBL60091

SMILES: OC(=O)[C@H]1C[C@H](NC(Nc2ccccc2)=NC#N)c2c(Cl)cc(Cl)cc2N1

InChI Key: InChIKey=HIZRZNHRCIBJRD-LSDHHAIUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005089   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005089 (4-anilino(imino-N-cyano)methylamino-5,7-dichloro-(...) Show SMILES OC(=O)[C@H]1C[C@H](NC(Nc2ccccc2)=NC#N)c2c(Cl)cc(Cl)cc2N1 |w:15.16| Show InChI InChI=1S/C18H15Cl2N5O2/c19-10-6-12(20)16-13(7-10)24-15(17(26)27)8-14(16)25-18(22-9-21)23-11-4-2-1-3-5-11/h1-7,14-15,24H,8H2,(H,26,27)(H2,22,23,25)/t14-,15+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair