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BDBM50005233 2-({Acetyl-[5-(3,3-diphenyl-propoxy)-tetrahydro-furan-3-ylmethoxycarbonyl]-amino}-methyl)-1-ethyl-pyridinium; iodide::CHEMBL158907

SMILES: CC[n+]1ccccc1CN(C(C)=O)C(=O)OCC1COC(C1)OCCC(c1ccccc1)c1ccccc1

InChI Key: InChIKey=WSPFWOXBLPRUED-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50005233   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Platelet activating factor receptor


(Cavia porcellus)		BDBM50005233
PNG
(2-({Acetyl-[5-(3,3-diphenyl-propoxy)-tetrahydro-fu...)
Show SMILES CC[n+]1ccccc1CN(C(C)=O)C(=O)OCC1COC(C1)OCCC(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H37N2O5/c1-3-32-18-11-10-16-28(32)21-33(24(2)34)31(35)38-23-25-20-30(37-22-25)36-19-17-29(26-12-6-4-7-13-26)27-14-8-5-9-15-27/h4-16,18,25,29-30H,3,17,19-23H2,1-2H3/q+1
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Similars
PubMed
n/an/a 260n/an/an/an/an/an/a



J. Uriach & Cía.S.A.

Curated by ChEMBL


Assay Description
In vitro inhibition of PAF induced aggregation of rabbit platelets.

J Med Chem 35: 676-83 (1992)


BindingDB Entry DOI: 10.7270/Q298860P
More data for this
Ligand-Target Pair