BDBM50005263 4-(2-Amino-propyl)-2,5-dimethoxy-benzoic acid propyl ester::4-(2-Amino-propyl)-2,5-dimethoxy-benzoic acid propyl ester : (Hydrogen oxalate)::CHEMBL273251
SMILES: CCCOC(=O)c1cc(OC)c(CC(C)N)cc1OC
InChI Key: InChIKey=WCFHJUFPNNTMGG-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50005263 (4-(2-Amino-propyl)-2,5-dimethoxy-benzoic acid prop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as... | J Med Chem 35: 734-40 (1992) BindingDB Entry DOI: 10.7270/Q29K4BV4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin 2 (5-HT2) receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM50005263 (4-(2-Amino-propyl)-2,5-dimethoxy-benzoic acid prop...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor of rat frontal cortex using [3H]ketanserin radioligand | J Med Chem 33: 1032-6 (1990) BindingDB Entry DOI: 10.7270/Q2319Z37 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50005263 (4-(2-Amino-propyl)-2,5-dimethoxy-benzoic acid prop...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards 5-hydroxytryptamine 1C receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]mesulergine ... | J Med Chem 35: 734-40 (1992) BindingDB Entry DOI: 10.7270/Q29K4BV4 | |||||||||||
More data for this Ligand-Target Pair |