BDBM50005809 CHEMBL35555::[2-(1H-Indol-3-yl)-1-methyl-1-(phenethylamino-methyl)-ethyl]-carbamic acid adamantan-2-yl ester;0.75H2O
SMILES: CC(CNCCc1ccccc1)(Cc1c[nH]c2ccccc12)NC(=O)OC1[C@H]2C[C@@H]3C[C@@H](C[C@H]1C3)C2
InChI Key: InChIKey=JZUOVJILJZOLCD-BEQISFSGSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholecystokinin receptor (RAT) | BDBM50005809 (CHEMBL35555 | [2-(1H-Indol-3-yl)-1-methyl-1-(phene...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Neuroscience Research Center Curated by ChEMBL | Assay Description Inhibition of [125I]CCK-8 binding to Cholecystokinin type A receptor in the rat pancreas | J Med Chem 35: 1472-84 (1992) BindingDB Entry DOI: 10.7270/Q2H41S3W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cholecystokinin receptor (MOUSE) | BDBM50005809 (CHEMBL35555 | [2-(1H-Indol-3-yl)-1-methyl-1-(phene...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Parke-Davis Neuroscience Research Center Curated by ChEMBL | Assay Description Inhibition of [125I]CCK-8 binding to cholecystokinin type B receptor in the mouse cerebral cortex | J Med Chem 35: 1472-84 (1992) BindingDB Entry DOI: 10.7270/Q2H41S3W | |||||||||||
More data for this Ligand-Target Pair |