BDBM50006464 CHEMBL303210::[4-Methyl-6-oxo-1-(5-trifluoromethyl-benzothiazol-2-ylmethyl)-1,6-dihydro-pyridazin-3-yl]-acetic acid
SMILES: Cc1cc(=O)n(Cc2nc3cc(ccc3s2)C(F)(F)F)nc1CC(O)=O
InChI Key: InChIKey=RNDNMIOYEBTJDS-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Aldose reductase (AR) (Homo sapiens (Human)) | BDBM50006464![]() (CHEMBL303210 | [4-Methyl-6-oxo-1-(5-trifluoromethy...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc Curated by ChEMBL | Assay Description Inhibitory activity against aldose reductase isolated from human placenta | J Med Chem 35: 2155-62 (1992) BindingDB Entry DOI: 10.7270/Q2KK99RR | |||||||||||
More data for this Ligand-Target Pair |