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SMILES: OC(=O)Cc1nn(Cc2nc3ccccc3s2)c2ccc(Cl)cc12

InChI Key: InChIKey=AXNXAQSAOLDTLD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50006483   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Homo sapiens (Human))		BDBM50006483
PNG
((1-Benzothiazol-2-ylmethyl-5-chloro-1H-indazol-3-y...)
Show SMILES OC(=O)Cc1nn(Cc2nc3ccccc3s2)c2ccc(Cl)cc12
Show InChI InChI=1S/C17H12ClN3O2S/c18-10-5-6-14-11(7-10)13(8-17(22)23)20-21(14)9-16-19-12-3-1-2-4-15(12)24-16/h1-7H,8-9H2,(H,22,23)
PDB

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PubMed
n/an/a 58n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibitory activity against aldose reductase isolated from human placenta

J Med Chem 35: 2155-62 (1992)


BindingDB Entry DOI: 10.7270/Q2KK99RR
More data for this
Ligand-Target Pair