BDBM50006697 8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-dione::CHEMBL33115
SMILES: CCCn1c2nc(CCc3ccccc3)[nH]c2c(=O)n(CCC)c1=O
InChI Key: InChIKey=CIDAIWBSWSWBOW-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50006697 (8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of N6-[3H]-cyclohexyladenosine binding to adenosine A1 receptor from rat cortical membranes | J Med Chem 35: 2342-5 (1992) BindingDB Entry DOI: 10.7270/Q2T43S20 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A1 (Rattus norvegicus (rat)) | BDBM50006697 (8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 58 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nova Pharmaceutical Corporation Curated by ChEMBL | Assay Description Binding affinity against adenosine A1 receptor in rat cortex by the displacement of [3H]-cyclohexyladenosine (CHA). | J Med Chem 34: 1431-5 (1991) BindingDB Entry DOI: 10.7270/Q2G73CP1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine A1 receptor (GUINEA PIG) | BDBM50006697 (8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL | Assay Description Binding affinity against adenosine A1 receptor from guinea pig forebrain membranes, using N6-[3H]-cyclohexyladenosine as radioligand. | J Med Chem 35: 2342-5 (1992) BindingDB Entry DOI: 10.7270/Q2T43S20 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50006697 (8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 593 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of N-[3H]-ethyladenosin-5''-uronamide binding to adenosine A2 receptor from rat striatal membranes | J Med Chem 35: 2342-5 (1992) BindingDB Entry DOI: 10.7270/Q2T43S20 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50006697 (8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 593 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nova Pharmaceutical Corporation Curated by ChEMBL | Assay Description Binding affinity against adenosine A2 receptor in rat striatum by the displacement of [3H]N-ethyladenosine-5''-uronamide(NECA). | J Med Chem 34: 1431-5 (1991) BindingDB Entry DOI: 10.7270/Q2G73CP1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine A2 receptor (Rattus norvegicus-Rattus norvegicus (rat)) | BDBM50006697 (8-Phenethyl-1,3-dipropyl-3,7-dihydro-purine-2,6-di...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 6.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyowa Hakko Kogyo Co., Ltd Curated by ChEMBL | Assay Description Binding affinity against adenosine A2 receptor from rat striatal membranes, using N-[3H]-ethyladenosin-5''-uronamide as radioligand (in the presence ... | J Med Chem 35: 2342-5 (1992) BindingDB Entry DOI: 10.7270/Q2T43S20 | |||||||||||
More data for this Ligand-Target Pair |