BDBM50007083 3-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-benzoic acid::3-hydroxy-4-(4-(2-nitrovinyl)phenoxysulfonyl)benzoic acid::CHEMBL77688

SMILES: OC(=O)c1ccc(c(O)c1)[S+]([O-])(=O)Oc1ccc(\C=C\[N+]([O-])=O)cc1

InChI Key: InChIKey=HQLCXHBEEVAKPL-BQYQJAHWSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50007083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase transforming protein Abl (Abelson murine leukemia virus)	BDBM50007083 (3-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...) Show SMILES OC(=O)c1ccc(c(O)c1)[S+]([O-])(=O)Oc1ccc(\C=C\[N+]([O-])=O)cc1 Show InChI InChI=1S/C15H11NO8S/c17-13-9-11(15(18)19)3-6-14(13)25(22,23)24-12-4-1-10(2-5-12)7-8-16(20)21/h1-9H,(H2-,17,18,19,22,23)/b8-7+	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Abelson murine leukemia virus p60 v-abl				J Nat Prod 55: 1529-1560 (1992) Article DOI: 10.1021/np50089a001 BindingDB Entry DOI: 10.7270/Q2J966CC
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL (Homo sapiens (Human))	BDBM50007083 (3-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...) Show SMILES OC(=O)c1ccc(c(O)c1)[S+]([O-])(=O)Oc1ccc(\C=C\[N+]([O-])=O)cc1 Show InChI InChI=1S/C15H11NO8S/c17-13-9-11(15(18)19)3-6-14(13)25(22,23)24-12-4-1-10(2-5-12)7-8-16(20)21/h1-9H,(H2-,17,18,19,22,23)/b8-7+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Ltd. Curated by ChEMBL					Assay Description Inhibition of recombinant v-Abl tyrosine kinase.				J Med Chem 34: 2328-37 (1991) BindingDB Entry DOI: 10.7270/Q24F1RB9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50007083 (3-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...) Show SMILES OC(=O)c1ccc(c(O)c1)[S+]([O-])(=O)Oc1ccc(\C=C\[N+]([O-])=O)cc1 Show InChI InChI=1S/C15H11NO8S/c17-13-9-11(15(18)19)3-6-14(13)25(22,23)24-12-4-1-10(2-5-12)7-8-16(20)21/h1-9H,(H2-,17,18,19,22,23)/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Ciba-Geigy Ltd. Curated by ChEMBL					Assay Description Inhibition of the epidermal growth factor receptor expressed in A431 cell line				J Med Chem 34: 2328-37 (1991) BindingDB Entry DOI: 10.7270/Q24F1RB9
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50007083 (3-Hydroxy-4-[4-(2-nitro-vinyl)-phenoxysulfonyl]-be...) Show SMILES OC(=O)c1ccc(c(O)c1)[S+]([O-])(=O)Oc1ccc(\C=C\[N+]([O-])=O)cc1 Show InChI InChI=1S/C15H11NO8S/c17-13-9-11(15(18)19)3-6-14(13)25(22,23)24-12-4-1-10(2-5-12)7-8-16(20)21/h1-9H,(H2-,17,18,19,22,23)/b8-7+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of EGFR in human A431 cells				J Nat Prod 55: 1529-1560 (1992) Article DOI: 10.1021/np50089a001 BindingDB Entry DOI: 10.7270/Q2J966CC
					More data for this Ligand-Target Pair