BDBM50007204 CHEMBL3237872

SMILES: [H][C@@]12C[C@@]([H])(C1(C)C)[C@]1(C)OB(O[C@]1([H])C2)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)NC)NC(C)=O

InChI Key: InChIKey=PJAVIPGUMNKCGD-HRVVITOKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50007204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-7 (Homo sapiens (Human))	BDBM50007204 (CHEMBL3237872) Show SMILES [H][C@@]12C[C@@]([H])(C1(C)C)[C@]1(C)OB(O[C@]1([H])C2)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)NC)NC(C)=O |r| Show InChI InChI=1S/C22H38BN3O5/c1-12(2)8-18(26-20(29)15(25-13(3)27)11-19(28)24-7)23-30-17-10-14-9-16(21(14,4)5)22(17,6)31-23/h12,14-18H,8-11H2,1-7H3,(H,24,28)(H,25,27)(H,26,29)/t14-,15-,16-,17+,18-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of caspase-like activity of human 20S proteasome using Ac-nLPnLD-AMC as substrate				J Med Chem 57: 2726-35 (2014) Article DOI: 10.1021/jm500045x BindingDB Entry DOI: 10.7270/Q24M961D
					More data for this Ligand-Target Pair
Proteasome subunit beta type-7 (Homo sapiens (Human))	BDBM50007204 (CHEMBL3237872) Show SMILES [H][C@@]12C[C@@]([H])(C1(C)C)[C@]1(C)OB(O[C@]1([H])C2)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)NC)NC(C)=O |r| Show InChI InChI=1S/C22H38BN3O5/c1-12(2)8-18(26-20(29)15(25-13(3)27)11-19(28)24-7)23-30-17-10-14-9-16(21(14,4)5)22(17,6)31-23/h12,14-18H,8-11H2,1-7H3,(H,24,28)(H,25,27)(H,26,29)/t14-,15-,16-,17+,18-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human 20S proteasome using Suc-LLVY-AMC as substrate				J Med Chem 57: 2726-35 (2014) Article DOI: 10.1021/jm500045x BindingDB Entry DOI: 10.7270/Q24M961D
					More data for this Ligand-Target Pair
Proteasome subunit beta type-7 (Homo sapiens (Human))	BDBM50007204 (CHEMBL3237872) Show SMILES [H][C@@]12C[C@@]([H])(C1(C)C)[C@]1(C)OB(O[C@]1([H])C2)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)NC)NC(C)=O |r| Show InChI InChI=1S/C22H38BN3O5/c1-12(2)8-18(26-20(29)15(25-13(3)27)11-19(28)24-7)23-30-17-10-14-9-16(21(14,4)5)22(17,6)31-23/h12,14-18H,8-11H2,1-7H3,(H,24,28)(H,25,27)(H,26,29)/t14-,15-,16-,17+,18-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of trypsin-like activity of human 20S proteasome using Ac-RLR-AMC as substrate				J Med Chem 57: 2726-35 (2014) Article DOI: 10.1021/jm500045x BindingDB Entry DOI: 10.7270/Q24M961D
					More data for this Ligand-Target Pair