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BDBM50007339 CHEMBL109115::N-(2-Methyl-1-pyrrolidin-1-ylmethyl-propyl)-2-phenyl-N-propyl-acetamide

SMILES: CCCN([C@H](CN1CCCC1)C(C)C)C(=O)Cc1ccccc1

InChI Key: InChIKey=BJHZCCULJAFEHN-LJQANCHMSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007339   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kappa-type opioid receptor


(Cavia porcellus (domestic guinea pig))		BDBM50007339
PNG
(CHEMBL109115 | N-(2-Methyl-1-pyrrolidin-1-ylmethyl...)
Show SMILES CCCN([C@H](CN1CCCC1)C(C)C)C(=O)Cc1ccccc1
Show InChI InChI=1S/C20H32N2O/c1-4-12-22(20(23)15-18-10-6-5-7-11-18)19(17(2)3)16-21-13-8-9-14-21/h5-7,10-11,17,19H,4,8-9,12-16H2,1-3H3/t19-/m1/s1
PDB

UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 1.44E+3n/an/an/an/an/an/a



ICI Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligand

J Med Chem 34: 3149-58 (1991)


BindingDB Entry DOI: 10.7270/Q2028S53
More data for this
Ligand-Target Pair