BDBM50007348 2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-methyl-1-methylaminomethyl-propyl)-acetamide::CHEMBL107358

SMILES: CNC[C@H](C(C)C)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=AVOVCWHTBKAYRG-CQSZACIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007348   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007348 (2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-methyl-1-met...) Show SMILES CNC[C@H](C(C)C)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2O/c1-10(2)14(9-18-3)19(4)15(20)8-11-5-6-12(16)13(17)7-11/h5-7,10,14,18H,8-9H2,1-4H3/t14-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	625	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligand				J Med Chem 34: 3149-58 (1991) BindingDB Entry DOI: 10.7270/Q2028S53
					More data for this Ligand-Target Pair