BDBM50007358 CHEMBL107652::N-Methyl-N-(2-methyl-1-pyrrolidin-1-ylmethyl-propyl)-3-phenyl-propionamide

SMILES: CC(C)[C@@H](CN1CCCC1)N(C)C(=O)CCc1ccccc1

InChI Key: InChIKey=ZAJKDVKEEBHKIH-GOSISDBHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50007358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50007358 (CHEMBL107652 | N-Methyl-N-(2-methyl-1-pyrrolidin-1...) Show SMILES CC(C)[C@@H](CN1CCCC1)N(C)C(=O)CCc1ccccc1 Show InChI InChI=1S/C19H30N2O/c1-16(2)18(15-21-13-7-8-14-21)20(3)19(22)12-11-17-9-5-4-6-10-17/h4-6,9-10,16,18H,7-8,11-15H2,1-3H3/t18-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
ICI Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligand				J Med Chem 34: 3149-58 (1991) BindingDB Entry DOI: 10.7270/Q2028S53
					More data for this Ligand-Target Pair