BDBM50008179 4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(4-isopropyl-benzoylamino)-butyric acid::CHEMBL124155

SMILES: CC(C)c1ccc(cc1)C(=O)NC(CCC(O)=O)C(=O)NN1CCC2(CCCC2)CC1

InChI Key: InChIKey=QILDUUBHILTMNL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008179   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50008179 (4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(4-isoprop...) Show SMILES CC(C)c1ccc(cc1)C(=O)NC(CCC(O)=O)C(=O)NN1CCC2(CCCC2)CC1 Show InChI InChI=1S/C24H35N3O4/c1-17(2)18-5-7-19(8-6-18)22(30)25-20(9-10-21(28)29)23(31)26-27-15-13-24(14-16-27)11-3-4-12-24/h5-8,17,20H,3-4,9-16H2,1-2H3,(H,25,30)(H,26,31)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair
CCKBR (RAT)	BDBM50008179 (4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-(4-isoprop...) Show SMILES CC(C)c1ccc(cc1)C(=O)NC(CCC(O)=O)C(=O)NN1CCC2(CCCC2)CC1 Show InChI InChI=1S/C24H35N3O4/c1-17(2)18-5-7-19(8-6-18)22(30)25-20(9-10-21(28)29)23(31)26-27-15-13-24(14-16-27)11-3-4-12-24/h5-8,17,20H,3-4,9-16H2,1-2H3,(H,25,30)(H,26,31)(H,28,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair