BDBM50008180 4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(naphthalene-2-carbonyl)-amino]-butyric acid::CHEMBL125925

SMILES: OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1

InChI Key: InChIKey=RCDATCVHPIFQKB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50008180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50008180 (4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(naphth...) Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1 Show InChI InChI=1S/C26H33N3O4/c30-23(31)11-10-22(27-24(32)21-9-8-19-6-2-3-7-20(19)18-21)25(33)28-29-16-14-26(15-17-29)12-4-1-5-13-26/h2-3,6-9,18,22H,1,4-5,10-17H2,(H,27,32)(H,28,33)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Concentration required to inhibit by 50% the specific binding of [3H]pentagastrin to CCK-B in rabbit gastric gland				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair
CCKBR (RAT)	BDBM50008180 (4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(naphth...) Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1 Show InChI InChI=1S/C26H33N3O4/c30-23(31)11-10-22(27-24(32)21-9-8-19-6-2-3-7-20(19)18-21)25(33)28-29-16-14-26(15-17-29)12-4-1-5-13-26/h2-3,6-9,18,22H,1,4-5,10-17H2,(H,27,32)(H,28,33)(H,30,31)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50008180 (4-(3-Aza-spiro[5.5]undec-3-ylcarbamoyl)-4-[(naphth...) Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCCC2)CC1 Show InChI InChI=1S/C26H33N3O4/c30-23(31)11-10-22(27-24(32)21-9-8-19-6-2-3-7-20(19)18-21)25(33)28-29-16-14-26(15-17-29)12-4-1-5-13-26/h2-3,6-9,18,22H,1,4-5,10-17H2,(H,27,32)(H,28,33)(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair