BDBM50008182 4-(2,3-Dichloro-benzoylamino)-4-(3,3-dimethyl-butylcarbamoyl)-butyric acid::CHEMBL124378

SMILES: CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1cccc(Cl)c1Cl

InChI Key: InChIKey=UDCLQTAISUBDFD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008182   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (RAT)	BDBM50008182 (4-(2,3-Dichloro-benzoylamino)-4-(3,3-dimethyl-buty...) Show SMILES CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1cccc(Cl)c1Cl Show InChI InChI=1S/C18H24Cl2N2O4/c1-18(2,3)9-10-21-17(26)13(7-8-14(23)24)22-16(25)11-5-4-6-12(19)15(11)20/h4-6,13H,7-10H2,1-3H3,(H,21,26)(H,22,25)(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Inhibition of [125I](BH)-CCK-8 binding to cholecystokinin type A receptor in rat pancreatic acini; Inactive				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair
CCKBR (RAT)	BDBM50008182 (4-(2,3-Dichloro-benzoylamino)-4-(3,3-dimethyl-buty...) Show SMILES CC(C)(C)CCNC(=O)C(CCC(O)=O)NC(=O)c1cccc(Cl)c1Cl Show InChI InChI=1S/C18H24Cl2N2O4/c1-18(2,3)9-10-21-17(26)13(7-8-14(23)24)22-16(25)11-5-4-6-12(19)15(11)20/h4-6,13H,7-10H2,1-3H3,(H,21,26)(H,22,25)(H,23,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair