BDBM50008211 4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-[(naphthalene-2-carbonyl)-amino]-butyric acid::CHEMBL339453

SMILES: OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCC2)CC1

InChI Key: InChIKey=FDOWAHFNCKHPNF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CCKBR (RAT)	BDBM50008211 (4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-[(naphthal...) Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCC2)CC1 Show InChI InChI=1S/C25H31N3O4/c29-22(30)10-9-21(24(32)27-28-15-13-25(14-16-28)11-3-4-12-25)26-23(31)20-8-7-18-5-1-2-6-19(18)17-20/h1-2,5-8,17,21H,3-4,9-16H2,(H,26,31)(H,27,32)(H,29,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50008211 (4-(8-Aza-spiro[4.5]dec-8-ylcarbamoyl)-4-[(naphthal...) Show SMILES OC(=O)CCC(NC(=O)c1ccc2ccccc2c1)C(=O)NN1CCC2(CCCC2)CC1 Show InChI InChI=1S/C25H31N3O4/c29-22(30)10-9-21(24(32)27-28-15-13-25(14-16-28)11-3-4-12-25)26-23(31)20-8-7-18-5-1-2-6-19(18)17-20/h1-2,5-8,17,21H,3-4,9-16H2,(H,26,31)(H,27,32)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair