BDBM50008220 4-(2-Aza-spiro[4.5]dec-2-ylcarbamoyl)-4-(3,5-dichloro-benzoylamino)-butyric acid::CHEMBL339134

SMILES: OC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(C1)CCCCC2

InChI Key: InChIKey=RSNPJFMCBJYERY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50008220   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CCKBR (RAT)	BDBM50008220 (4-(2-Aza-spiro[4.5]dec-2-ylcarbamoyl)-4-(3,5-dichl...) Show SMILES OC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(C1)CCCCC2 Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-10-14(11-16(23)12-15)19(29)24-17(4-5-18(27)28)20(30)25-26-9-8-21(13-26)6-2-1-3-7-21/h10-12,17H,1-9,13H2,(H,24,29)(H,25,30)(H,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Inhibition of the specific binding of [125I](BH)-CCK-8 to Cholecystokinin type B receptor in rat brain cortex				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair
Cholecystokinin receptor (RAT)	BDBM50008220 (4-(2-Aza-spiro[4.5]dec-2-ylcarbamoyl)-4-(3,5-dichl...) Show SMILES OC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(C1)CCCCC2 Show InChI InChI=1S/C21H27Cl2N3O4/c22-15-10-14(11-16(23)12-15)19(29)24-17(4-5-18(27)28)20(30)25-26-9-8-21(13-26)6-2-1-3-7-21/h10-12,17H,1-9,13H2,(H,24,29)(H,25,30)(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Rotta Research Laboratorium Curated by ChEMBL					Assay Description Concentration required to inhibit by 50% specific binding of [125I](BH)-CCK-8 to cholecystokinin type A receptor in rat pancreatic acini				J Med Chem 35: 28-38 (1992) BindingDB Entry DOI: 10.7270/Q2XS5W11
					More data for this Ligand-Target Pair