BDBM50008464 CHEMBL143231::[4-Oxo-3-(3-phenyl-[1,2,4]oxadiazol-5-ylmethyl)-3,4-dihydro-phthalazin-1-yl]-acetic acid

SMILES: OC(=O)Cc1nn(Cc2nc(no2)-c2ccccc2)c(=O)c2ccccc12

InChI Key: InChIKey=FQELKXJYAGISES-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008464   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50008464 (CHEMBL143231 | [4-Oxo-3-(3-phenyl-[1,2,4]oxadiazol...) Show SMILES OC(=O)Cc1nn(Cc2nc(no2)-c2ccccc2)c(=O)c2ccccc12 Show InChI InChI=1S/C19H14N4O4/c24-17(25)10-15-13-8-4-5-9-14(13)19(26)23(21-15)11-16-20-18(22-27-16)12-6-2-1-3-7-12/h1-9H,10-11H2,(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against aldose reductase isolated from human placenta				J Med Chem 35: 457-65 (1992) BindingDB Entry DOI: 10.7270/Q28051K1
					More data for this Ligand-Target Pair