BDBM50008473 CHEMBL140042::[4-Oxo-3-(5-phenyl-oxazol-2-ylmethyl)-3,4-dihydro-phthalazin-1-yl]-acetic acid

SMILES: OC(=O)Cc1nn(Cc2ncc(o2)-c2ccccc2)c(=O)c2ccccc12

InChI Key: InChIKey=KPUWBWBNAUTTPX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human))	BDBM50008473 (CHEMBL140042 | [4-Oxo-3-(5-phenyl-oxazol-2-ylmethy...) Show SMILES OC(=O)Cc1nn(Cc2ncc(o2)-c2ccccc2)c(=O)c2ccccc12 Show InChI InChI=1S/C20H15N3O4/c24-19(25)10-16-14-8-4-5-9-15(14)20(26)23(22-16)12-18-21-11-17(27-18)13-6-2-1-3-7-13/h1-9,11H,10,12H2,(H,24,25)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description In vitro inhibitory activity against aldose reductase isolated from human placenta				J Med Chem 35: 457-65 (1992) BindingDB Entry DOI: 10.7270/Q28051K1
					More data for this Ligand-Target Pair