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SMILES: OC(=O)Cc1nn(Cc2cc(ns2)-c2ccccc2)c(=O)c2ccccc12

InChI Key: InChIKey=RQSXAKYHCNGAIH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50008477   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aldo-keto reductase family 1 member B1


(Homo sapiens (Human))		BDBM50008477
PNG
(CHEMBL357435 | [4-Oxo-3-(3-phenyl-isothiazol-5-ylm...)
Show SMILES OC(=O)Cc1nn(Cc2cc(ns2)-c2ccccc2)c(=O)c2ccccc12
Show InChI InChI=1S/C20H15N3O3S/c24-19(25)11-18-15-8-4-5-9-16(15)20(26)23(21-18)12-14-10-17(22-27-14)13-6-2-1-3-7-13/h1-10H,11-12H2,(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 670n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against aldose reductase isolated from human placenta

J Med Chem 35: 457-65 (1992)


BindingDB Entry DOI: 10.7270/Q28051K1
More data for this
Ligand-Target Pair