BDBM50009268 CHEMBL3233197

SMILES: Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

InChI Key: InChIKey=GKVLXSNNBUSNOA-XWGVYQGASA-N

Data: 2 KI  3 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50009268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50009268 (CHEMBL3233197) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C27H33N5O4/c1-15-10-18(33)11-16(2)20(15)13-21(28)27(36)32-9-5-8-24(32)26(35)31-23(25(29)34)12-17-14-30-22-7-4-3-6-19(17)22/h3-4,6-7,10-11,14,21,23-24,30,33H,5,8-9,12-13,28H2,1-2H3,(H2,29,34)(H,31,35)/t21-,23-,24-/m0/s1	PDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing Medical University Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membranes				Bioorg Med Chem 22: 2208-19 (2014) Article DOI: 10.1016/j.bmc.2014.02.015 BindingDB Entry DOI: 10.7270/Q29Z96DB
					More data for this Ligand-Target Pair
Opioid receptors; mu & delta (Rattus norvegicus (rat))	BDBM50009268 (CHEMBL3233197) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C27H33N5O4/c1-15-10-18(33)11-16(2)20(15)13-21(28)27(36)32-9-5-8-24(32)26(35)31-23(25(29)34)12-17-14-30-22-7-4-3-6-19(17)22/h3-4,6-7,10-11,14,21,23-24,30,33H,5,8-9,12-13,28H2,1-2H3,(H2,29,34)(H,31,35)/t21-,23-,24-/m0/s1	PDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing Medical University Curated by ChEMBL					Assay Description Displacement of [3H]deltorphin-2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membranes				Bioorg Med Chem 22: 2208-19 (2014) Article DOI: 10.1016/j.bmc.2014.02.015 BindingDB Entry DOI: 10.7270/Q29Z96DB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50009268 (CHEMBL3233197) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C27H33N5O4/c1-15-10-18(33)11-16(2)20(15)13-21(28)27(36)32-9-5-8-24(32)26(35)31-23(25(29)34)12-17-14-30-22-7-4-3-6-19(17)22/h3-4,6-7,10-11,14,21,23-24,30,33H,5,8-9,12-13,28H2,1-2H3,(H2,29,34)(H,31,35)/t21-,23-,24-/m0/s1	PDB NCI pathway Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a
Nanjing Medical University Curated by ChEMBL					Assay Description Agonist activity at GFP-fused mu opioid receptor (unknown origin) expressed in HEK293 cells assessed as recruitment of beta-arrestin-2 after 10 mins ...				Bioorg Med Chem 22: 2208-19 (2014) Article DOI: 10.1016/j.bmc.2014.02.015 BindingDB Entry DOI: 10.7270/Q29Z96DB
					More data for this Ligand-Target Pair
Delta-type opioid receptor (MOUSE)	BDBM50009268 (CHEMBL3233197) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C27H33N5O4/c1-15-10-18(33)11-16(2)20(15)13-21(28)27(36)32-9-5-8-24(32)26(35)31-23(25(29)34)12-17-14-30-22-7-4-3-6-19(17)22/h3-4,6-7,10-11,14,21,23-24,30,33H,5,8-9,12-13,28H2,1-2H3,(H2,29,34)(H,31,35)/t21-,23-,24-/m0/s1	PDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing Medical University Curated by ChEMBL					Assay Description Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction				Bioorg Med Chem 22: 2208-19 (2014) Article DOI: 10.1016/j.bmc.2014.02.015 BindingDB Entry DOI: 10.7270/Q29Z96DB
					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50009268 (CHEMBL3233197) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C27H33N5O4/c1-15-10-18(33)11-16(2)20(15)13-21(28)27(36)32-9-5-8-24(32)26(35)31-23(25(29)34)12-17-14-30-22-7-4-3-6-19(17)22/h3-4,6-7,10-11,14,21,23-24,30,33H,5,8-9,12-13,28H2,1-2H3,(H2,29,34)(H,31,35)/t21-,23-,24-/m0/s1	B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing Medical University Curated by ChEMBL					Assay Description Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contraction				Bioorg Med Chem 22: 2208-19 (2014) Article DOI: 10.1016/j.bmc.2014.02.015 BindingDB Entry DOI: 10.7270/Q29Z96DB
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50009268 (CHEMBL3233197) Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI InChI=1S/C27H33N5O4/c1-15-10-18(33)11-16(2)20(15)13-21(28)27(36)32-9-5-8-24(32)26(35)31-23(25(29)34)12-17-14-30-22-7-4-3-6-19(17)22/h3-4,6-7,10-11,14,21,23-24,30,33H,5,8-9,12-13,28H2,1-2H3,(H2,29,34)(H,31,35)/t21-,23-,24-/m0/s1	PDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing Medical University Curated by ChEMBL					Assay Description Agonist activity at delta opioid receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation af...				Bioorg Med Chem 22: 2208-19 (2014) Article DOI: 10.1016/j.bmc.2014.02.015 BindingDB Entry DOI: 10.7270/Q29Z96DB
					More data for this Ligand-Target Pair