BindingDB PrimarySearch

BDBM50010267 CHEMBL92719::[2-(4-Hydroxy-phenyl)-ethyl]-carbamic acid (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-dodecahydro-benzo[f]chromen-6-yl ester::[2-(4-Hydroxy-phenyl)-ethyl]-carbamic acid 5,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyl-dodecahydro-benzo[f]chromen-6-yl ester

SMILES: CC1(C)CC[C@H](O)[C@@]2(C)[C@H]1[C@H](OC(=O)NCCc1ccc(O)cc1)[C@H](O)[C@@]1(C)O[C@](C)(CC(=O)[C@]21O)C=C

InChI Key: InChIKey=RLAXBRLFWGMJNW-JTOWCYLCSA-N

Data: 2 IC50 2 Kd 1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50010267
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenylate cyclase type I (Bos taurus)	BDBM50010267 (CHEMBL92719 \| [2-(4-Hydroxy-phenyl)-ethyl]-carbami...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Displacement of [125I]-6-IHPP-Fsk from adenylate cyclase of bovine brain membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
Food and Drug Administration Curated by ChEMBL					More data for this Ligand-Target Pair
Glucose Transporter 1 (hGLUT1) (Homo sapiens (Human))	BDBM50010267 (CHEMBL92719 \| [2-(4-Hydroxy-phenyl)-ethyl]-carbami...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Inhibition of [125I]-7-IHPP-Fsk binding to glucose transporter of human erythrocyte membrane				J Med Chem 34: 3204-12 (1991) BindingDB Entry DOI: 10.7270/Q20C4TRQ
Food and Drug Administration Curated by ChEMBL					More data for this Ligand-Target Pair
Adenylate cyclase (Homo sapiens (Human))	BDBM50010267 (CHEMBL92719 \| [2-(4-Hydroxy-phenyl)-ethyl]-carbami...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	630	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Conversion of [32P] ATP to [32P]-cyclic AMP mediated by adenylate cyclase 1				J Med Chem 39: 2745-52 (1996) Article DOI: 10.1021/jm960191+ BindingDB Entry DOI: 10.7270/Q2X34WJG
Food and Drug Administration Curated by ChEMBL					More data for this Ligand-Target Pair
Adenylate cyclase (Homo sapiens (Human))	BDBM50010267 (CHEMBL92719 \| [2-(4-Hydroxy-phenyl)-ethyl]-carbami...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>150	n/a	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1				J Med Chem 39: 2745-52 (1996) Article DOI: 10.1021/jm960191+ BindingDB Entry DOI: 10.7270/Q2X34WJG
Food and Drug Administration Curated by ChEMBL					More data for this Ligand-Target Pair
Adenylate cyclase (Homo sapiens (Human))	BDBM50010267 (CHEMBL92719 \| [2-(4-Hydroxy-phenyl)-ethyl]-carbami...) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a	n/a
Food and Drug Administration Curated by ChEMBL					Assay Description Inhibition of [125 I]-6-IHPP-forskolin binding to adenylate cyclase 1				J Med Chem 39: 2745-52 (1996) Article DOI: 10.1021/jm960191+ BindingDB Entry DOI: 10.7270/Q2X34WJG
Food and Drug Administration Curated by ChEMBL					More data for this Ligand-Target Pair