BDBM50010867 1-[1-(3-Bromo-phenyl)-2-dimethylamino-ethyl]-cyclohexanol (HCl)::CHEMBL319142
SMILES: CN(C)CC(c1cccc(Br)c1)C1(O)CCCCC1
InChI Key: InChIKey=GGTQWEXXJQVGJS-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Norepinephrine Monoamine transporters (Rattus norvegicus) | BDBM50010867![]() (1-[1-(3-Bromo-phenyl)-2-dimethylamino-ethyl]-cyclo...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomes | J Med Chem 33: 2899-905 (1990) BindingDB Entry DOI: 10.7270/Q20C4WCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat)) | BDBM50010867![]() (1-[1-(3-Bromo-phenyl)-2-dimethylamino-ethyl]-cyclo...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Inhibition of binding of [3H]imipramine to imipramine receptor in rat brain | J Med Chem 33: 2899-905 (1990) BindingDB Entry DOI: 10.7270/Q20C4WCM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50010867![]() (1-[1-(3-Bromo-phenyl)-2-dimethylamino-ethyl]-cyclo...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth-Ayerst Research Curated by ChEMBL | Assay Description Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomes | J Med Chem 33: 2899-905 (1990) BindingDB Entry DOI: 10.7270/Q20C4WCM | |||||||||||
More data for this Ligand-Target Pair |