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BDBM50011203 CHEMBL143143::CHEMBL3349880::Sodium; 7-[3,4-dibromo-2-(4-fluoro-phenyl)-5-isopropyl-pyrrol-1-yl]-3,5-dihydroxy-heptanoate

SMILES: [Na+].CC(C)c1c(Br)c(Br)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O

InChI Key: InChIKey=XKACIQXLWLWJBV-YSSOQSIOSA-M

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011203   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
HMG-CoA reductase


(Rattus norvegicus (rat))		BDBM50011203
PNG
(CHEMBL3349880 | Sodium; 7-[3,4-dibromo-2-(4-fluoro...)
Show SMILES [Na+].CC(C)c1c(Br)c(Br)c(-c2ccc(F)cc2)n1CC[C@@H](O)C[C@@H](O)CC([O-])=O
Show InChI InChI=1S/C20H24Br2FNO4/c1-11(2)19-17(21)18(22)20(12-3-5-13(23)6-4-12)24(19)8-7-14(25)9-15(26)10-16(27)28/h3-6,11,14-15,25-26H,7-10H2,1-2H3,(H,27,28)/p-1/t14?,15-/m1/s1
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PubMed
n/an/a 26n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Ability to inhibit microsomal preparation of HMG-CoA reductase in rat liver.

J Med Chem 34: 463-6 (1991)


BindingDB Entry DOI: 10.7270/Q2MS3TC4
More data for this
Ligand-Target Pair