BDBM50011755 1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.1]heptane-2,4-dione::CHEMBL26543

SMILES: Nc1ccc(cc1)C12CC(C1)C(=O)NC2=O

InChI Key: InChIKey=CZWGXZRCYVSEOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50011755   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 19A1 (Homo sapiens (Human))	BDBM50011755 (1-(4-Amino-phenyl)-3-aza-bicyclo[3.1.1]heptane-2,4...) Show SMILES Nc1ccc(cc1)C12CC(C1)C(=O)NC2=O |(8.22,.27,;6.89,-.5,;5.54,.28,;4.2,-.47,;4.21,-2.01,;5.54,-2.8,;6.88,-2.04,;2.88,-2.78,;1.55,-2.01,;.23,-2.78,;1.56,-3.55,;.23,-4.32,;-1.11,-5.09,;1.55,-5.09,;2.88,-4.32,;4.21,-5.09,)| Show InChI InChI=1S/C12H12N2O2/c13-9-3-1-8(2-4-9)12-5-7(6-12)10(15)14-11(12)16/h1-4,7H,5-6,13H2,(H,14,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA-GEIGY AG. Curated by ChEMBL					Assay Description In vitro inhibition of human placental Cytochrome P450 19A aromatase				J Med Chem 34: 1329-34 (1991) BindingDB Entry DOI: 10.7270/Q2QN65RW
					More data for this Ligand-Target Pair