BDBM50011955 2-[2-(1H-Indol-3-yl)-ethyl]-3-(3-trifluoromethyl-phenyl)-3H-quinazolin-4-one::CHEMBL37439

SMILES: FC(F)(F)c1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O

InChI Key: InChIKey=LCPFOKSQZRDCHH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gastrin/cholecystokinin type B receptor (Homo sapiens (Human))	BDBM50011955 (2-[2-(1H-Indol-3-yl)-ethyl]-3-(3-trifluoromethyl-p...) Show SMILES FC(F)(F)c1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H18F3N3O/c26-25(27,28)17-6-5-7-18(14-17)31-23(30-22-11-4-2-9-20(22)24(31)32)13-12-16-15-29-21-10-3-1-8-19(16)21/h1-11,14-15,29H,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-labeled gastrin binding to gastrin/cholecystokinin type B receptor				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50011955 (2-[2-(1H-Indol-3-yl)-ethyl]-3-(3-trifluoromethyl-p...) Show SMILES FC(F)(F)c1cccc(c1)-n1c(CCc2c[nH]c3ccccc23)nc2ccccc2c1=O Show InChI InChI=1S/C25H18F3N3O/c26-25(27,28)17-6-5-7-18(14-17)31-23(30-22-11-4-2-9-20(22)24(31)32)13-12-16-15-29-21-10-3-1-8-19(16)21/h1-11,14-15,29H,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-CCK-8 sulfate binding to cholecystokinin type B receptor in mouse brain membranes.				J Med Chem 34: 1505-8 (1991) BindingDB Entry DOI: 10.7270/Q2Z60N1P
					More data for this Ligand-Target Pair