BDBM50011974 3-[2-Butyl-3-(2-nitro-benzyl)-3H-imidazol-4-yl]-2-thiophen-2-ylmethyl-acrylic acid::CHEMBL291086

SMILES: CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1[N+]([O-])=O

InChI Key: InChIKey=ZQIOEYNQFIXWJE-SFQUDFHCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50011974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (RAT)	BDBM50011974 (3-[2-Butyl-3-(2-nitro-benzyl)-3H-imidazol-4-yl]-2-...) Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C22H23N3O4S/c1-2-3-10-21-23-14-18(12-17(22(26)27)13-19-8-6-11-30-19)24(21)15-16-7-4-5-9-20(16)25(28)29/h4-9,11-12,14H,2-3,10,13,15H2,1H3,(H,26,27)/b17-12+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of [125I]AII binding to Angiotensin II receptor, type 1 of rat mesenteric arteries				J Med Chem 36: 1880-92 (1993) BindingDB Entry DOI: 10.7270/Q2PK0JC7
					More data for this Ligand-Target Pair
Angiotensin II AT2 (RAT)	BDBM50011974 (3-[2-Butyl-3-(2-nitro-benzyl)-3H-imidazol-4-yl]-2-...) Show SMILES CCCCc1ncc(\C=C(/Cc2cccs2)C(O)=O)n1Cc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C22H23N3O4S/c1-2-3-10-21-23-14-18(12-17(22(26)27)13-19-8-6-11-30-19)24(21)15-16-7-4-5-9-20(16)25(28)29/h4-9,11-12,14H,2-3,10,13,15H2,1H3,(H,26,27)/b17-12+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of [125I]-AII specific binding towards Angiotensin II receptor in rat mesenteric membranes.				J Med Chem 34: 1514-7 (1991) BindingDB Entry DOI: 10.7270/Q2TD9WBV
					More data for this Ligand-Target Pair